منابع مشابه
Rhinovirus-Induced Exacerbations of Asthma and COPD
Over the past two decades, increasing evidence has shown that, in patients with chronic airways disease, viral infection is the most common cause of exacerbation. This review will examine the evidence for viral-induced exacerbations of asthma and chronic obstructive lung disease and the potential mechanisms by which viruses cause exacerbations. Attention will be focused on rhinovirus, the most ...
متن کاملRhinovirus-induced interferon production in asthma.
After reading the article by Sykes et al, we would like to comment on impaired response to rhinovirus in relation to asthma severity. The authors examined rhinovirus-induced interferon (IFN) production in a cohort of asthmatic patients compared with controls. While they previously reported in this population a reduced IFN production in cells from bronchoalveolar lavage, they fail to document su...
متن کاملAssociation of rhinovirus infections with asthma.
Rhinoviruses are the most common cause of the common cold, but they can cause more severe illnesses in people with underlying lung disorders such as asthma, chronic obstructive pulmonary disease, or cystic fibrosis. Epidemiologic studies with sensitive detection methods such as PCR have identified rhinovirus infection as a major source of asthma exacerbations in both children and adults, especi...
متن کاملModels and mechanisms of exercise-induced asthma.
Airflow-induced bronchoconstriction (AIB) in mammals can be broadly categorized as either vagal-dependent or vagal-independent. Among mammals, rabbits and cats belong to the former and guinea-pigs belong to the latter categories. Although insufficient data are available to classify monkeys, dogs and man appear to occupy the middle ground in which a small but significant parasympathetic componen...
متن کاملHeterogeneity of mechanisms in exercise induced asthma.
The development of airflow limitation that occurs in 70-80% of people with asthma several minutes after vigorous exercise is known as exercise induced asthma. In most asthmatic patients the airflow obstruction is reversed spontaneously within 60 minutes. There are, however, asthmatic individuals who have more prolonged airways obstruction and who require bronchodilator treatment to recover pre-...
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ژورنال
عنوان ژورنال: Paediatric Respiratory Reviews
سال: 2004
ISSN: 1526-0542
DOI: 10.1016/j.prrv.2004.04.002